poRe: an R package for the visualization and analysis of nanopore sequencing data
نویسندگان
چکیده
MOTIVATION The Oxford Nanopore MinION device represents a unique sequencing technology. As a mobile sequencing device powered by the USB port of a laptop, the MinION has huge potential applications. To enable these applications, the bioinformatics community will need to design and build a suite of tools specifically for MinION data. RESULTS Here we present poRe, a package for R that enables users to manipulate, organize, summarize and visualize MinION nanopore sequencing data. As a package for R, poRe has been tested on Windows, Linux and MacOSX. Crucially, the Windows version allows users to analyse MinION data on the Windows laptop attached to the device. AVAILABILITY AND IMPLEMENTATION poRe is released as a package for R at http://sourceforge.net/projects/rpore/. A tutorial and further information are available at https://sourceforge.net/p/rpore/wiki/Home/.
منابع مشابه
Studying Performance of Dubinin-astakhov and Dubinin-raduchkevic Equations to Evaluate Nanopore Volume and Pore Size of MCM-41 Particles (TECHNICAL NOTE)
MCM-41 particles were synthesized using inorganic raw materials and Cetyltrimethylammonium bromide (CTAB). The textural properties and structure of MCM-41 particles were characterized by XRD, SEM, TEM and N2 adsorption-desorption methods. To study performance of Dubinin-Astakhov and Dubinin-Raduchkevic isotherm models in evaluating mesopore volume and pore size of MCM-41 samples, the mesopore ...
متن کاملOptimized Tree-Type Cylindrical-Shaped Nanoporous Filtering Membranes with 6 or 7 Branch Pores in each Pore Tree
The performances of the optimized tree-type cylindrical-shaped nanoporous fltering membranes with six or seven branch pores in each pore tree are analytically studied. The radius Rb,1 of the branch pore for fltration is normally on the 1 or 10 nm scales. The larger trunk pore is for ...
متن کاملInvestigation of the Performance of an Optimized Tree-Type Cylindrical-Shaped Nanoporous Filtering Membrane for Varying Operational Parameter Values
The performance of an optimized tree-type cylindrical-shaped nanoporous fltering membrane proposed in the former study is analytically investigated for varying operational parameter values. Across the membrane thickness, this membrane has two-leveled tree-structured pores including one trunk pore and the multiple branch pores. The physical properties of the surfaces of ...
متن کاملHybrid pore formation by directed insertion of α-haemolysin into solid-state nanopores.
Most experiments on nanopores have concentrated on the pore-forming protein α-haemolysin (αHL) and on artificial pores in solid-state membranes. While biological pores offer an atomically precise structure and the potential for genetic engineering, solid-state nanopores offer durability, size and shape control, and are also better suited for integration into wafer-scale devices. However, each s...
متن کاملPoretools: a toolkit for analyzing nanopore sequence data
MOTIVATION Nanopore sequencing may be the next disruptive technology in genomics, owing to its ability to detect single DNA molecules without prior amplification, lack of reliance on expensive optical components, and the ability to sequence long fragments. The MinION™ from Oxford Nanopore Technologies (ONT) is the first nanopore sequencer to be commercialized and is now available to early-acces...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 31 شماره
صفحات -
تاریخ انتشار 2015